Презентация на тему: Medical protozoology: Apicomplexa

Medical protozoology: Apicomplexa
A note on taxonomy
Morphology-based taxonomy
Morphology-based taxonomy
Morphology-based taxonomy
Morphology-based taxonomy
Parasitic Apicomplexa (former Sporozoa )
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Parasitic Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
Medical protozoology: Apicomplexa
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Первый слайд презентации: Medical protozoology: Apicomplexa

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Слайд 2: A note on taxonomy

Adl et al. 2012 The revised classification of eukaryotes. The Journal of Eukaryotic Microbiology. 59(2), 429 – 493. Taxonomy  is the science of defining groups of biological organisms on the basis of shared characteristics and giving names to those groups. Practical application Understanding evolution of life

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Слайд 3: Morphology-based taxonomy

Depending on the locomotion mode protozoa divided into four major groups: Phylum Flagellates (move by means of flagella)

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Слайд 4: Morphology-based taxonomy

Depending on the locomotion mode protozoa divided into four major groups: Phylum Amoebae (by pseudopodia)

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Слайд 5: Morphology-based taxonomy

Depending on the locomotion mode protozoa divided into four major groups: Phylum Ciliates (by cilia)

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Слайд 6: Morphology-based taxonomy

Depending on the locomotion mode protozoa divided into four major groups: Phylum Sporozoa (lacking any obvious means of locomotion)

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Слайд 7: Parasitic Apicomplexa (former Sporozoa )

The apicomplexa are a monophyletic group composed almost entirely of parasitic ( ie, no free-living) species. Apicomplexa, along with ciliates and dinoflagellates, form a higher order group known as Alveolata. A major defining characteristic of the this group are flattened vesicle-like structures, called cortical alveolae, which are found just underneath the plasma membrane. Formerly the apicomplexa were part of a group called Sporozoa and this name is still sometimes used.

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Слайд 8: Parasitic Apicomplexa

A defining characteristic of the apicomplexa is a group of organelles found at one end--called the apical end--of the organism. This is a type of plastid called an  apicoplast, and anapical complex  structure involved in penetrating a host's cell.

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Слайд 9: Parasitic Apicomplexa

This 'apical complex' includes secretory organelles known as micronemes and rhoptries, polar rings composed of microtubules, and in some species a conoid which lies within the polar rings.

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Слайд 10: Parasitic Apicomplexa

At some point during their life cycle, members of the apicomplexa either invade or attach to host cells. It is during this invasive (and/or motile) stage that these apical organelles are expressed as well as the subpellicular membranes, which are actually cortical alveoli. The apical organelles play a role in interaction of the parasite with the host cell and the subsequent invasion of the host cell. Motile forms of apicomplexa crawl along the substratum in a non-ameboid fashion known as gliding motility. Many apicomplexan species have flagellated gametes.

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Слайд 11: Parasitic Apicomplexa

The apicomplexa have complex life cycles that are characterized by three distinct processes: sporogony, merogony and gametogony.

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Слайд 12: Parasitic Apicomplexa

Although most apicomplexa exhibit this overall general life cycle the details can vary between species. Furthermore, the terminology used to describe these various life cycle stages vary between the species. The life cycle consists of both asexually reproducing forms and sexual stages.

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Слайд 13: Parasitic Apicomplexa

In monoxenous species all three of these processes will be carried out in a single host and often in a single cell type or tissue. Whereas, in heteroxenous species the various processes will be carried out in different hosts and generally involve different tissues.

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Слайд 14: Parasitic Apicomplexa

Sporogony occurs immediately after a sexual phase and consists of an asexual reproduction that culminates in the production of sporozoites. Sporozoites are an invasive form that will invade cells and develop into forms that undergo another asexual replication known as merogony.

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Слайд 15: Parasitic Apicomplexa

Merogony and the resulting merozoites are known by many different names depending of the species. In contrast to sporogony, in which there is generally only one round of replication, quite often there are multiple rounds of merogony. In other words, the merozoites, which are also invasive forms, can reinvade cells and initiate another round of merogony.

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Слайд 16: Parasitic Apicomplexa

As an alternative to asexual replication merozoites can develop into gametes through a process variously called gametogony, gamogony or gametogenesis. As in other types of sexual reproduction, the gametes fuse to form a zygote which will undergo sporogony.

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Слайд 17: Parasitic Apicomplexa

The apicomplexa are an extremely large and diverse group (>5000 named species). Seven species infect humans. Plasmodium Babesia Cryptosporidium Isospora Cyclospora Sarcocystis Toxoplasma

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Слайд 18: Parasitic Apicomplexa

Plasmodium, as the causative agent of malaria, has the greatest impact on human health. Babesia is a relatively rare zoonotic infection. The other five species are all classified as coccidia. However, recent molecular data indicates that Cryptosporidium is more closely related to the gregarines than to the coccidia. The coccidia are generally considered opportunistic pathogens and are often associated with AIDS.

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Слайд 19: Parasitic Apicomplexa

Several apicomplexan parasites are also important in terms of veterinary medicine and agriculture. Most notable are Babesia and Theileria in cattle and Eimeria in poultry.

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Слайд 20: Parasitic Apicomplexa

Diseases caused by apicomplexan organisms include, but are not limited to: Forms of coccidiosis including: Cryptosporidiosis (Cryptosporidium parvum) Cyclosporiasis (Cyclospora cayetanensis) Isosporiasis (Isospora belli) Toxoplasmosis (Toxoplasma gondii) Malaria ( Plasmodium ) Babesiosis ( Babesia )

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