Первый слайд презентации: CRIMEA STATE MEDICAL UNIVERSITY
Class-15 Phylogenic disorders of heart GUIDED BY: MISS ANNA PRESENTED BY : VASU
Слайд 2: What is phylogenetics ?
Phylogenetics is the study of evolutionary relationships among biological entities - often species, individuals or genes It is based on the phylogenetic hypothesis that all living organisms share a common ancestry. The relationships among organisms are depicted in what is known as a phylogenetic tree. the phylogeny shows the evolutionary history of the individuals. This concept also makes sense for sequences coming from the same individual, as in our case of using phylogeny for reconstructing the haplotype sequences from genotypes
Слайд 3: Phylogenetic heart disorders of heart
arrhythmias, congenital heart disease, cardiomyopathy, high blood cholesterol There are a number of inherited disorders that can cause arrhythmias and sudden cardiac death.
Слайд 4: Common factors of arrhythmias
Atrial fibrillation: a common arrhythmia that increases the risk for stroke Brugada Syndrome: a genetic disorder of the heart rhythm that can cause ventricular fibrillation and sudden cardiac arrest Long QT Syndrome: a prolonged electrical recovery phase (QT interval) of the heartbeat that can result in rapid, chaotic beats Short QT Syndrome: a shortened QT interval that can result in life-threatening arrhythmias
Слайд 5: ARRHYTHMIA
An arrhythmia is a problem with the rate or rhythm of your heartbeat. It means that your heart beats too quickly, too slowly, or with an irregular pattern. When the heart beats faster than normal, it is called tachycardia.
Слайд 6: CONGENITAL HEART DISEASE
Problems with genes or chromosomes in the child, such as Down syndrome. Taking certain medications, or alcohol or drug abuse during pregnancy. A viral infection, like rubella (German measles) in the mother in the first trimester of pregnancy
Слайд 7: CARDIOMYOPATHY
Cardiomyopathy is a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body. Cardiomyopathy can lead to heart failure. The main types of cardiomyopathy include dilated, hypertrophic and restrictive cardiomyopathy.
Слайд 8: Diagnosis of Cardiomyopathy
Shortness of breath or trouble breathing, especially with physical exertion Fatigue Swelling in the ankles, feet, legs, abdomen and veins in the neck Dizziness Lightheadedness Fainting during physical activity
Слайд 10: Brugada syndrome
Brugada syndrome is a genetic disorder in which the electrical activity within the heart is abnormal. It increases the risk of abnormal heart rhythms and sudden cardiac death. The abnormal heart rhythms seen in those with Brugada syndrome often occur at rest. They may be triggered by a fever.
Слайд 12: Catecholaminergic polymorphic ventricular tachycardia
Catecholaminergic polymorphic ventricular tachycardia is a condition characterized by an abnormal heart rhythm. As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast and irregular heartbeat called ventricular tachycardia. Polymorphic Ventricular Tachycardia. Polymorphic VT associated with a normal QT interval is most often caused by acute ischemia or infarction and may rapidly degenerate into VF.
Слайд 13: Long QT syndrome
Long QT syndrome (LQTS) is a condition in which repolarization of the heart after a heartbeat is affected. It results in an increased risk of an irregular heartbeat which can result in fainting, drowning, seizures, or sudden death. These episodes can be triggered by exercise or stress. Causes: Genetic, certain medications, low blood Symptoms: Fainting, hearing loss, seizures Treatment: Avoiding strenuous exercise,
Слайд 14: Short Q-T syndrome
Short QT syndrome is a very rare genetic disease of the electrical system of the heart, and is associated with an increased risk of abnormal heart rhythms and sudden cardiac death. The syndrome gets its name from a characteristic feature seen on an electrocardiogram (ECG) – a shortening of the QT interval Short QT syndrome is a genetic disorder caused by mutations in genes responsible for producing certain ion channels within heart cells. It appears to be inherited in an autosomal dominant pattern